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KMID : 0882419940470060861
Korean Journal of Medicine
1994 Volume.47 No. 6 p.861 ~ p.865
Multifocal Chloromas in AML
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Abstract
Granulocytic sarcoma, or chloroma is a localized extramedullary tumor mass composed of immature cells of the granulocytic series.
It was first described by Burns in 1811, subsequently termed "Chloroma" because of green color sometimes imparted by cellular myeloperoxidase. Dock was the first to note the association of granulocytic sarcoma with acute leukemia, it may by
associated
with such myeloproliferative disorder as hypereosinoplilia, polycythemia vera, or myeloid metaplasia. Granulocytic sarcoma is now regarded as an omnious habinger of acute myelocytic leukemia (AML), or the onset of blast crisis in chronic
myelogeneous
leukemia (CML).
Granulocytic sarcoma can arise in various locations including the periosteum of the bones, lymph nodes, skin, epidural structures, female genitalia, gonads, breast, gastrointestinal tract, urinary bladder, and kidney. Although its overall
incidence
is
low, the tumor can present in any organ.
We report a case of a 18-year-old man who was diagnosed as having multifocal granulo cytic sarcoma in the soft tissue.
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